SCHEMBL11162467

SCHEMBL11162467

CCCCCCCC(C)(C)c1ccc(Br)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 17/20 0.62
CNR2 P34972 17/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11161641 1.00 CNR1 (0.62) CNR1CNR2
SCHEMBL11167872 1.00 CNR1 (0.62) CNR1CNR2
SCHEMBL11165168 1.00 CNR1 (0.62) CNR1CNR2
SCHEMBL4888798 1.00 CNR1 (0.62) CNR1CNR2
SCHEMBL11168100 0.98 CNR1 (0.59) CNR1CNR2
SCHEMBL11170831 0.94 CNR1 (0.54) CNR1CNR2
SCHEMBL11166331 0.87 CNR1 (0.50) CNR1CNR2
SCHEMBL420915 0.83 CNR1 (0.64) CNR1CNR2
SCHEMBL10927244 0.83 CNR1 (0.63) CNR1CNR2
SCHEMBL8654061 0.81 CNR2 (0.68) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4391827-A 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor PFIZER INC. (US) 1983-07-05 US disclosed
US-4387229-A ANALGESICS, TRANQUILIZERS, SEDATIVES PFIZER INC. (US) 1983-06-07 US disclosed
US-4332942-A 3-(2-Hydroxy-4-(substituted)phenyl)azacycloalkanes as analgesics PFIZER, INC. (US) 1982-06-01 US disclosed
US-4306097-A 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents PFIZER INC. (US) 1981-12-15 US disclosed
US-4284829-A Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives PFIZER INC. (US) 1981-08-18 US disclosed
US-4283569-A Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives PFIZER INC. (US) 1981-08-11 US disclosed
US-4263438-A 3-[2,4-(Disubstituted)-phenyl]azacycloalkanones as analgesics PFIZER INC. (US) 1981-04-21 US disclosed
US-4147872-A 3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor PFIZER INC. (US) 1979-04-03 US disclosed