Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.50 |
| ▸ | CNR2 | P34972 | 14/20 | 0.50 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170831 | 0.90 | CNR1 (0.54) | CNR1CNR2ESR1ESR2 | |
| SCHEMBL11168100 | 0.88 | CNR1 (0.59) | CNR1CNR2 | |
| SCHEMBL11167872 | 0.87 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL4888798 | 0.87 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL11161641 | 0.87 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL11162467 | 0.87 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL11165168 | 0.87 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL11162634 | 0.85 | MAPK1 (0.42) | CNR1CNR2ESR1ESR2AR | |
| SCHEMBL21654058 | 0.81 | ESR1 (0.43) | CNR1CNR2ESR1ESR2AR | |
| SCHEMBL23059294 | 0.79 | CNR1 (0.50) | CNR1CNR2ESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391827-A | 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor | PFIZER INC. (US) | 1983-07-05 | — | — | US | disclosed |
| US-4306097-A | 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |