Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 14/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GALR3 | O60755 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175054 | 0.88 | PDE3B (0.62) | PDE3BPDE3AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11172793 | 0.87 | PDE3B (0.61) | PDE3BPDE3AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11171962 | 0.86 | PDE3B (0.68) | PDE3BPDE3AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11167091 | 0.86 | PDE3B (0.60) | PDE3BPDE3AMAPTGALR3THRB | |
| SCHEMBL11159556 | 0.85 | PDE3B (0.59) | PDE3BPDE3AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11161927 | 0.83 | PDE3B (0.76) | PDE3BPDE3AMAPTGALR3THRB | |
| SCHEMBL11165225 | 0.81 | PDE3B (0.70) | PDE3BPDE3AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11165047 | 0.81 | PDE3B (0.77) | PDE3BPDE3AMAPTGALR3THRB | |
| SCHEMBL11120072 | 0.80 | PDE3B (0.62) | PDE3BPDE3AMAPTGALR3THRB | |
| SCHEMBL11167698 | 0.78 | PDE3B (0.66) | PDE3BPDE3AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415571-A | HYPOTENSIVE AGENTS; THROMBOSIS; ANTICOAGULANTS; CARDIOVASCULAR DISORDDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |