Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774171 | 0.80 | CYP1A2 (0.49) | TDP1MAPTCYP1A2ALDH1A1TSHR | |
| SCHEMBL10717343 | 0.78 | TSHR (0.50) | TDP1MAPTCYP1A2ALDH1A1TSHR | |
| SCHEMBL10779738 | 0.76 | TSHR (0.43) | TDP1MAPTHTTALDH1A1GAA | |
| SCHEMBL287937 | 0.74 | PTGS2 (0.41) | TSHRHTR2C | |
| SCHEMBL2728751 | 0.74 | TDP1 (0.50) | TDP1CYP1A2ALDH1A1TSHRCASP6 | |
| SCHEMBL30527915 | 0.74 | TDP1 (0.50) | TDP1CYP1A2ALDH1A1TSHRCASP6 | |
| Benzene SCHEMBL9443154 | 0.73 | TDP1 (0.57) | TDP1ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL2431833 | 0.72 | CYP1A2 (0.63) | TDP1MAPTCYP1A2ALDH1A1TSHR | |
| SCHEMBL2431836 | 0.72 | CYP1A2 (0.63) | TDP1MAPTCYP1A2ALDH1A1TSHR | |
| SCHEMBL28256134 | 0.72 | TDP1 (0.61) | TDP1CYP1A2ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028609-B1 | USE OF CHLORONITROPHENYL DERIVATIVES AS SELECTIVE HERBICIDES AND NEW CHLORONITROPHENYL DERIVATIVES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1983-07-27 | — | — | EP | disclosed |
| EP-0028609-A1 | Use of chloronitrophenyl derivatives as selective herbicides and new chloronitrophenyl derivatives. | SIEGFRIED AG (CH) | 1981-05-20 | — | — | EP | disclosed |
| WO-1980002493-A1 | HERBICIDES | SIEGFRIED AG (CH) | 1980-11-27 | — | — | WO | disclosed |