Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166713 | 1.00 | AKR1C3 (0.71) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL11162808 | 0.91 | AKR1C3 (0.67) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL11156323 | 0.88 | MAPT (0.66) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL11156326 | 0.88 | MAPT (0.66) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL11329421 | 0.87 | L3MBTL1 (0.60) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL10942207 | 0.84 | MAPK1 (0.63) | AKR1C3AKR1C2MAPTAKR1B1AKR1C4 | |
| SCHEMBL11157458 | 0.84 | MAPT (0.51) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL11157453 | 0.84 | MAPT (0.51) | AKR1C3AKR1C2MAPTAKR1B10AKR1B1 | |
| SCHEMBL11467579 | 0.84 | MAPK1 (0.63) | AKR1C3AKR1C2MAPTAKR1B1AKR1C4 | |
| SCHEMBL11473772 | 0.84 | MAPK1 (0.61) | AKR1C3AKR1C2MAPTAKR1B1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013144-B1 | SUBSTITUTED DIPHENYLAMINE DERIVATIVES, COMPOSITIONS AND HERBICIDAL USES THEREOF, AND PROCESSES FOR THEIR PREPARATION | ICI AUSTRALIA LIMITED (AU) | 1983-02-23 | — | — | EP | claimed |