Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 13/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029542 | 0.83 | CYP4F2 (0.56) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL8225438 | 0.83 | SIGMAR1 (0.42) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL10984090 | 0.83 | KCNN4 (0.42) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL3168557 | 0.83 | KCNN4 (0.41) | KCNN4KCNH2TMEM97SIGMAR1 | |
| SCHEMBL8226253 | 0.83 | KCNN4 (0.43) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL4444828 | 0.83 | KCNN4 (0.41) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL14405811 | 0.80 | KCNH2 (0.46) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL12093364 | 0.80 | KCNH2 (0.40) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL4431632 | 0.80 | KCNN4 (0.43) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 | |
| SCHEMBL13547891 | 0.80 | KCNH2 (0.43) | KCNN4KCNH2TMEM97SIGMAR1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079167-A1 | A carbapenem compound, preparation and use | BEECHAM GROUP PLC (GB) | 1983-05-18 | — | — | EP | disclosed |