SCHEMBL11170648

SCHEMBL11170648

C(CCCC1CCCNC1)CCC1CCCNC1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.51
NAAA Q02083 1/20 0.50
HRH4 Q9H3N8 2/20 0.46
KMT2A Q03164 1/20 0.45
SIGMAR1 Q99720 3/20 0.41
CPN1 P15169 1/20 0.41
CPB2 Q96IY4 1/20 0.41
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
ACP1 P24666 2/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
EPHX1 P07099 1/20 0.37
EED O75530 3/20 0.36
NPY1R P25929 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704486 0.93 HRH3 (0.53) HRH3NAAAHRH4KMT2ACPN1
SCHEMBL28741956 0.90 CYP1A2 (0.47) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL19578854 0.90 CYP1A2 (0.47) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL12557625 0.90 NAAA (0.48) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL7593657 0.90 CYP1A2 (0.47) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL8948236 0.90 CYP1A2 (0.47) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL6198775 0.90 HRH3 (0.45) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL4303428 0.90 NAAA (0.48) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL22857512 0.90 CYP1A2 (0.47) HRH3NAAAHRH4KMT2ASIGMAR1
SCHEMBL19286087 0.90 CYP1A2 (0.47) HRH3NAAAHRH4KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4391812-A ANTIINFLAMMATORY AGENTS MERCK & CO., INC. (US) 1983-07-05 US disclosed
US-4342872-A ANTIMICROBIAL AGENTS MERCK & CO., INC. (US) 1982-08-03 US disclosed
US-4342873-A MICROBIOCIDES MERCK & CO., INC. (US) 1982-08-03 US disclosed
US-4247700-A MICROBIOCIDES MERCK & CO., INC. (US) 1981-01-27 US disclosed