Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.45 |
| ▸ | CDC25B | P30305 | 5/20 | 0.45 |
| ▸ | GJB2 | P29033 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAG | P20916 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173059 | 0.94 | TP53 (0.52) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL18241603 | 0.92 | TP53 (0.53) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL5840927 | 0.92 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL16967451 | 0.92 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL5840884 | 0.92 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15514084 | 0.92 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL11494535 | 0.91 | MAG (0.49) | TP53MDM2POLBLGALS3MAG | |
| SCHEMBL11170198 | 0.91 | MAG (0.49) | TP53MDM2POLBLGALS3MAG | |
| SCHEMBL11170193 | 0.91 | MAG (0.49) | TP53MDM2POLBLGALS3MAG | |
| SCHEMBL7582210 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391800-A | Immunologically active peptidyl disaccharides and methods of preparation | MERCK & CO., INC. (US) | 1983-07-05 | — | — | US | disclosed |
| EP-0018901-B1 | IMMUNOLOGICALLY ACTIVE PEPTIDYL DISACCHARIDES, METHODS OF PREPARATION AND VACCINE | MERCK & CO. INC. (US) | 1982-12-15 | — | — | EP | disclosed |