Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.49 |
| ▸ | CDC25B | P30305 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840927 | 0.97 | TP53 (0.55) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL16967451 | 0.97 | TP53 (0.55) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL15514084 | 0.97 | TP53 (0.55) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL5840884 | 0.97 | TP53 (0.55) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL11173059 | 0.93 | TP53 (0.52) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL13491599 | 0.93 | POLB (0.52) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL7583524 | 0.93 | POLB (0.52) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL16628842 | 0.92 | L3MBTL1 (0.58) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL16628841 | 0.92 | L3MBTL1 (0.58) | TP53MDM2POLBMDM4HSP90AA1 | |
| SCHEMBL6760496 | 0.91 | POLB (0.63) | TP53MDM2POLBMDM4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137791-A1 | NEURAMINIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR MEDICAL USE | SANKYO COMPANY, LIMITED (JP) | 2002-09-26 | — | — | US | disclosed |
| US-6451766-B1 | SIALIDASE INHIBITORS; INFLUENZA VIRICIDES | SANKYO COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |
| US-6340702-B1 | SIALIDASE INHIBITORS; ANTIVIRAL COMPOUNDS | SANKYO COMPANY, LIMITED (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0823428-B1 | Neuraminic acid derivatives, their preparation and their medical use | SANKYO CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0823428-A2 | Neuraminic acid derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1998-02-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137791-A1 | NEURAMINIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR MEDICAL USE | NEU1, NEU3, NEU2 | TP53 4767/4885MDM2 4193/4885POLB 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.