Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187623 | 0.77 | HSD17B10 (0.41) | HTR2AHTR2CHSD17B10KDM4EALOX15 | |
| SCHEMBL11183610 | 0.73 | CYP3A4 (0.41) | HSD17B10KDM4EALOX15MEN1KMT2A | |
| SCHEMBL11174540 | 0.72 | TP53 (0.39) | HSD17B10KDM4EALOX15MEN1KMT2A | |
| SCHEMBL11455502 | 0.72 | MAPKAPK2 (0.41) | HTR2AHTR2CHSD17B10KDM4EALOX15 | |
| SCHEMBL11185140 | 0.72 | HSD17B10 (0.39) | HTR2AHTR2CHSD17B10KDM4EALOX15 | |
| SCHEMBL11187463 | 0.72 | HSD17B10 (0.39) | HTR2AHTR2CHSD17B10KDM4EALOX15 | |
| SCHEMBL11445075 | 0.71 | MEN1 (0.37) | HTR2AHTR2CHSD17B10KDM4EALOX15 | |
| SCHEMBL11186247 | 0.71 | PDE5A (0.40) | HSD17B10KDM4EALOX15MEN1KMT2A | |
| SCHEMBL11186215 | 0.71 | CHRM2 (0.39) | HSD17B10KDM4EALOX15MAPK1MEN1 | |
| SCHEMBL11193303 | 0.70 | HSD17B10 (0.45) | HTR2AHTR2CHSD17B10KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389413-A | 9,11-Methano-13-aza-11a-carbathrombanoic acid analogues | ONO PHARMACEUTICAL CO. LTD. (JP) | 1983-06-21 | — | — | US | disclosed |
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| EP-0044711-A1 | 9,11-Methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-27 | — | — | EP | disclosed |