Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455502 | 0.86 | MAPKAPK2 (0.41) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| SCHEMBL11445324 | 0.85 | MAPKAPK2 (0.38) | MAPKAPK2CA1CA2CA4CA7 | |
| SCHEMBL11463557 | 0.83 | MEN1 (0.33) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| SCHEMBL11453418 | 0.79 | PDE1A (0.41) | MEN1KMT2AHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL10836067 | 0.71 | HSD17B10 (0.50) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| SCHEMBL11173309 | 0.71 | HTR2A (0.39) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| SCHEMBL11470919 | 0.69 | HSD17B10 (0.57) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL11469730 | 0.69 | HSD17B10 (0.60) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| SCHEMBL11070535 | 0.66 | CYP3A4 (0.46) | MEN1KMT2AHSD17B10HPGDCYP1A2 | |
| SCHEMBL10835113 | 0.65 | PDE1A (0.47) | MEN1KMT2AHSD17B10CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |