Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | AOC1 | P19801 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | LATS1 | O95835 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25451316 | 0.98 | EPHX1 (0.56) | EPHX1GAAMAPTLMNAPOLB | |
| SCHEMBL11498081 | 0.98 | EPHX1 (0.56) | EPHX1GAAMAPTLMNAPOLB | |
| SCHEMBL1726902 | 0.98 | EPHX1 (0.56) | EPHX1GAAMAPTLMNAPOLB | |
| Water SCHEMBL11247605 | 0.96 | EPHX1 (0.54) | EPHX1GAAMAPTLMNAPOLB | |
| SCHEMBL11169098 | 0.95 | EPHX1 (0.49) | EPHX1GAAMAPTLMNAPOLB | |
| SCHEMBL10372739 | 0.91 | CTSD (0.48) | EPHX1GAAMAPTLMNAPOLB | |
| SCHEMBL11526739 | 0.83 | MAPT (0.63) | GAAMAPTLMNAPOLBKDM4E | |
| SCHEMBL3960929 | 0.81 | HRH3 (0.47) | ROCK1HSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL30089543 | 0.81 | IRAK4 (0.50) | EPHX1S1PR1AOC1CTSDLATS1 | |
| SCHEMBL30089564 | 0.81 | MAPK1 (0.53) | EPHX1LMNAAOC3MAPK1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390710-A | A 4-AMINOPYRIDINE WITH A PYRIDINE | PPG INDUSTRIES, INC. (US) | 1983-06-28 | — | — | US | disclosed |
| US-4206215-A | Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes | STERLING DRUG INC. (US) | 1980-06-03 | — | — | US | disclosed |