Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27533325 | 0.98 | TP53 (0.31) | TP53TSHRSIRT2SIRT1 | |
| Hydrogen Sulfide SCHEMBL27531910 | 0.98 | TP53 (0.31) | TP53TSHRSIRT2SIRT1 | |
| Dimethylamine SCHEMBL4541945 | 0.92 | KDM4E (0.32) | — | |
| SCHEMBL5755219 | 0.84 | — | — | |
| SCHEMBL27387808 | 0.83 | — | — | |
| SCHEMBL7963362 | 0.81 | — | — | |
| SCHEMBL7380301 | 0.80 | HDAC1 (0.40) | — | |
| SCHEMBL28791650 | 0.79 | — | — | |
| SCHEMBL1117797 | 0.79 | POLB (0.31) | TSHR | |
| SCHEMBL11878406 | 0.79 | CA12 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900669-A1 | NEW BICYCLIC DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2015-08-05 | — | — | EP | claimed |
| CN-1980710-B | Substituted azepine derivatives as serotonin receptor modulators | ATHERSYS INC | 2013-06-12 | — | — | CN | claimed |
| WO-2010099166-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2010-09-02 | — | — | WO | claimed |
| EP-1987037-A2 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-11-05 | — | — | EP | claimed |
| WO-2007097470-A2 | FUSED NITROGEN- COMPRISING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-30 | — | — | WO | claimed |
| US-6323195-B1 | ENZYME INHIBITORS AND COGNITION ACTIVATORS | AVENTIS PHARMACEUTICALS INC. | 2001-11-27 | — | — | US | claimed |
| EP-1020470-A2 | Galanthamine derivatives, a process for their preparation and their use as medicaments | SYNAPTECH, INC. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-0653427-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-05-17 | — | — | EP | claimed |
| EP-0592512-A1 | NON-DESENSITIZING ANALOGS OF GnRH AND OTHER BIOLOGICALLY ACTIVE LIGANDS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (UTI) (CA) | 1994-04-20 | — | — | EP | claimed |
| WO-1993003058-A2 | NON-DESENSITIZING ANALOGS OF GnRH AND OTHER BIOLOGICALLY ACTIVE LIGANDS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1993-02-18 | — | — | WO | claimed |
| CN-1056878-A | 2-substituted alkyl-3-carboxycarbapenems as antibiotics and process for their preparation | AMERICAN CYANAMID CO (US) | 1991-12-11 | — | — | CN | claimed |
| EP-0058341-B1 | AZEPINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-05-15 | — | — | EP | claimed |
| EP-4525879-A2 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | Board of Regents, The University of Texas System (US) | 2025-03-26 | — | — | EP | disclosed |
| US-12124198-B2 | Image forming method and image forming apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2024-10-22 | — | — | US | disclosed |
| CN-118647605-A | Mesoionic arylpyridazinium derivatives or salts thereof, pesticides containing the same and methods of use thereof | 日本农药株式会社 | 2024-09-13 | — | — | CN | disclosed |
| WO-2024032561-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE (CDK) 12 AND/OR CDK13 AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-02-15 | — | — | WO | disclosed |
| WO-1994025049-A1 | AMIDINO AND GUANIDINO SUBSTITUTED BORONIC ACID INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
| EP-0356381-A1 | Wetting agents for hydrophobic capillary materials, and their uses | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| EP-0058341-B1 | AZEPINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-05-15 | — | — | EP | disclosed |
| EP-0058341-A1 | Azepine derivatives, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-08-25 | — | — | EP | disclosed |