⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387808 | 0.83 | — | — | |
| SCHEMBL1117697 | 0.81 | TP53 (0.32) | — | |
| SCHEMBL1117797 | 0.79 | POLB (0.31) | — | |
| SCHEMBL28015333 | 0.79 | CA5A (0.30) | — | |
| Water SCHEMBL27533325 | 0.79 | TP53 (0.31) | — | |
| Hydrogen Sulfide SCHEMBL27531910 | 0.79 | TP53 (0.31) | — | |
| SCHEMBL11878406 | 0.79 | CA12 (0.31) | — | |
| SCHEMBL28791650 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL10524813 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28642702 | 0.77 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323195-B1 | ENZYME INHIBITORS AND COGNITION ACTIVATORS | AVENTIS PHARMACEUTICALS INC. | 2001-11-27 | — | — | US | claimed |
| EP-1020470-A2 | Galanthamine derivatives, a process for their preparation and their use as medicaments | SYNAPTECH, INC. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-0653427-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-05-17 | — | — | EP | claimed |
| US-6323195-B1 | ENZYME INHIBITORS AND COGNITION ACTIVATORS | AVENTIS PHARMACEUTICALS INC. | 2001-11-27 | — | — | US | disclosed |
| EP-1020470-A2 | Galanthamine derivatives, a process for their preparation and their use as medicaments | SYNAPTECH, INC. (US) | 2000-07-19 | — | — | EP | disclosed |
| US-5777108-A | ALZHEIMER*S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0653427-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-05-17 | — | — | EP | disclosed |