Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 7/20 | 0.41 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031763 | 0.88 | MAOB (0.56) | MAOBCYP19A1MEN1KMT2AIMPDH2 | |
| SCHEMBL15970480 | 0.76 | BACE1 (0.60) | MAOBKMT2AAPPPTPN1BACE1 | |
| SCHEMBL14248288 | 0.76 | BACE1 (0.60) | MAOBKMT2AAPPPTPN1BACE1 | |
| SCHEMBL14160606 | 0.74 | IMPDH2 (0.52) | MAOBIMPDH2APPBACE1 | |
| SCHEMBL12866136 | 0.74 | MAOB (0.56) | MAOBCYP19A1MEN1KMT2AIMPDH2 | |
| SCHEMBL14160605 | 0.74 | IMPDH2 (0.49) | IMPDH2APP | |
| SCHEMBL11650628 | 0.72 | BACE1 (0.60) | MAOBKMT2AAPPPTPN1BACE1 | |
| SCHEMBL27160315 | 0.72 | BACE1 (0.60) | MAOBKMT2AAPPPTPN1BACE1 | |
| SCHEMBL27414810 | 0.72 | BACE1 (0.60) | MAOBKMT2AAPPPTPN1BACE1 | |
| SCHEMBL27414819 | 0.72 | BACE1 (0.60) | MAOBKMT2AAPPPTPN1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400545-A | ORGANOLEPTICS, FOODS, TOBACCO | FRITZSCHE DODGE & OLCOTT INC. (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0079989-A1 | Alicyclic ketone and alcohol derivatives | FRITZSCHE DODGE & OLCOTT INC. (US) | 1983-06-01 | — | — | EP | disclosed |
| US-4326997-A | Fragrance compositions of alicyclic ketone and alcohol derivatives | FRITZSCHE DODGE & OLCOTT INC. (US) | 1982-04-27 | — | — | US | disclosed |