Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191276 | 0.95 | MEN1 (0.37) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11199131 | 0.95 | MEN1 (0.37) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11175333 | 0.94 | MEN1 (0.38) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11178933 | 0.94 | MEN1 (0.36) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11200223 | 0.94 | MEN1 (0.36) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11173021 | 0.94 | MEN1 (0.36) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11189127 | 0.93 | MEN1 (0.36) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11180792 | 0.93 | MEN1 (0.36) | MEN1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL11265859 | 0.92 | PTGS2 (0.40) | CYP3A4LMNAPTGS1PTGS2KDM4E | |
| SCHEMBL11183009 | 0.90 | CYP3A4 (0.34) | MEN1KMT2ACYP3A4LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |