Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176308 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL12232362 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10KDM4EKDM6B | |
| SCHEMBL311876 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL5746936 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL13576813 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2HSD17B10KDM4E | |
| SCHEMBL25518086 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL7948512 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL10666955 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10SMN1; SMN2PGR | |
| SCHEMBL5171320 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10KDM4EKDM6B | |
| SCHEMBL12421785 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2KDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732935-B1 | LANTHANIDE CHELATES AND USE THEREOF IN BIOANALYSIS | SENSIENT IMAGING TECHNOLOGIES (DE) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007134117-A2 | DETECTING SINGLE AMINO ACID POLYMORPHISMS BY ISOTOPIC LABELING AND MASS SPECTROMETRY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2007-11-22 | — | — | WO | disclosed |
| US-4384144-A | Process for preparing cyclopentenone derivatives | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1983-05-17 | — | — | US | disclosed |