Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173367 | 0.77 | HCAR3 (0.42) | ALDH1A1KDM4ETDP1TSHRMAPT | |
| SCHEMBL11587382 | 0.76 | HCAR2 (0.34) | HCAR2ALDH1A1TDP1MAPK1CYP3A4 | |
| SCHEMBL28780392 | 0.75 | KDM4E (0.43) | HCAR2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL5612429 | 0.74 | HCAR2 (0.40) | HCAR2ALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL17797824 | 0.73 | TSHR (0.38) | HCAR2ALDH1A1TDP1TSHRCDC25B | |
| SCHEMBL28182584 | 0.73 | TSHR (0.38) | HCAR2ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL27933500 | 0.72 | IDO1 (0.41) | HCAR2PTGER4ALDH1A1KDM4EKMT2A | |
| SCHEMBL17797893 | 0.72 | TSHR (0.46) | HCAR2ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL153687 | 0.70 | TSHR (0.38) | HCAR2ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL27736079 | 0.69 | TSHR (0.52) | HCAR2ALDH1A1KDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369191-A | COMPLEMENT INHIBITION | AMERICAN CYANAMID COMPANY (US) | 1983-01-18 | — | — | US | disclosed |