SCHEMBL11178583

SCHEMBL11178583

CCCCCCCCCCCCCCCCCCOC1CC(C)(C)N(C(N)=O)C(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.39
GBA1 P04062 3/20 0.37
NAAA Q02083 1/20 0.34
SPHK1 Q9NYA1 2/20 0.34
CES2 O00748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408686 0.81 EPHX2 (0.39) EPHX2GBA1NAAA
SCHEMBL1889760 0.81 EPHX2 (0.42) EPHX2GBA1NAAACES2
SCHEMBL2435660 0.80 GBA1 (0.38) EPHX2GBA1NAAA
SCHEMBL26980319 0.80 GBA1 (0.42) EPHX2GBA1
SCHEMBL26977424 0.80 GBA1 (0.42) EPHX2GBA1
SCHEMBL6744101 0.80 GBA1 (0.38) EPHX2GBA1NAAA
SCHEMBL6298174 0.80 GBA1 (0.42) EPHX2GBA1
SCHEMBL11174237 0.78 GBA1 (0.39) EPHX2GBA1
SCHEMBL4259720 0.78 EPHX2 (0.38) EPHX2GBA1
SCHEMBL4347877 0.78 GBA1 (0.39) EPHX2GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed