SCHEMBL1889760

SCHEMBL1889760

CCCCCCCCCCCOC1CC(C)(C)N(OC(=O)ON2C(C)(C)CC(OCCCCCCCCCCC)CC2(C)C)C(C)(C)C1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 7/20 0.42
GBA1 P04062 2/20 0.38
TSHR P16473 2/20 0.35
KMT2A Q03164 1/20 0.35
NAAA Q02083 1/20 0.35
CES2 O00748 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ESR1 P03372 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15299847 0.83 GBA1 (0.37) EPHX2GBA1TSHRALDH1A1
SCHEMBL15299866 0.83 GBA1 (0.37) EPHX2GBA1TSHRALDH1A1
SCHEMBL27521048 0.81 GBA1 (0.36) EPHX2GBA1ALDH1A1
SCHEMBL6726712 0.81 GBA1 (0.36) EPHX2GBA1ALDH1A1
SCHEMBL2435660 0.81 GBA1 (0.38) EPHX2GBA1TSHRNAAAALDH1A1
SCHEMBL6744101 0.81 GBA1 (0.38) EPHX2GBA1TSHRNAAAALDH1A1
SCHEMBL26980319 0.81 GBA1 (0.42) EPHX2GBA1KMT2AALDH1A1
SCHEMBL26977424 0.81 GBA1 (0.42) EPHX2GBA1KMT2AALDH1A1
SCHEMBL6298174 0.81 GBA1 (0.42) EPHX2GBA1KMT2AALDH1A1
SCHEMBL11178583 0.81 EPHX2 (0.39) EPHX2GBA1NAAACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319882-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2013-10-09 EP disclosed
US-8288462-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2012-10-16 US disclosed
US-20110218279-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-09-08 US disclosed
EP-2319882-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2011-05-11 EP disclosed