Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11171212 | 0.99 | POLB (0.36) | POLBPGRDPP4MAPTTRPV1 | |
| Maleic Acid SCHEMBL11185760 | 0.93 | POLB (0.39) | POLBDPP4MAPTTP53MEN1 | |
| Hydrochloric Acid SCHEMBL11185605 | 0.81 | KMT2A (0.41) | DPP4MAPTTP53MEN1KMT2A | |
| SCHEMBL11173789 | 0.79 | BRD4 (0.51) | DPP4MAPTTP53KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11182898 | 0.78 | BRD4 (0.50) | DPP4MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL11173096 | 0.73 | MPO (0.47) | — | |
| Maleic Acid SCHEMBL11175151 | 0.73 | BRD4 (0.45) | PGRMAPTBRD4 | |
| Maleic Acid SCHEMBL11176338 | 0.73 | DPP4 (0.41) | POLBDPP4MAPTTP53MEN1 | |
| Cadaverine Tartrate SCHEMBL11175456 | 0.69 | MPO (0.41) | — | |
| SCHEMBL31140510 | 0.69 | KCNH2 (0.48) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393210-A | ANALGESIC, ANTIULCER, ANTIDEPRESSANT, ANTIHISTAMINE, ANTICHOLINERGIC | SEIYAKU CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |