Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.54 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.54 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465528 | 0.79 | ALDH1A1 (0.55) | MAPTGAAHTTLMNATHRB | |
| SCHEMBL11317580 | 0.79 | ALDH1A1 (0.58) | MAPTGAANPSR1PDE7AHTT | |
| SCHEMBL6244176 | 0.79 | ALDH1A1 (0.55) | MAPTGAAHTTLMNATHRB | |
| SCHEMBL29607775 | 0.78 | ALDH1A1 (0.44) | MAPTGAALMNATHRBALDH1A1 | |
| SCHEMBL19862412 | 0.78 | HSD17B10 (0.56) | MAPTGAANPSR1LMNAALDH1A1 | |
| SCHEMBL5693765 | 0.78 | ALDH1A1 (0.53) | MAPTGAAHTTLMNATHRB | |
| SCHEMBL22866211 | 0.78 | ALDH1A1 (0.44) | MAPTGAALMNATHRBALDH1A1 | |
| SCHEMBL29395878 | 0.76 | ALDH1A1 (0.55) | TXNRD1TXNRD3TXNRD2MAPTHTT | |
| SCHEMBL2123108 | 0.76 | ALDH1A1 (0.55) | TXNRD1TXNRD3TXNRD2MAPTHTT | |
| SCHEMBL16971064 | 0.76 | ALDH1A1 (0.58) | MAPTHTTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379784-A | ANTIBIOTICS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-04-12 | — | — | US | disclosed |