Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | GLI1 | P08151 | 4/20 | 0.37 |
| ▸ | GLI2 | P10070 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11171928 | 0.92 | PTGS1 (0.39) | KDM4EPTGS1PTGS2SMN1; SMN2PPARG | |
| SCHEMBL11271132 | 0.91 | PTGS2 (0.48) | KDM4EPTGS1PTGS2GLI1GLI2 | |
| SCHEMBL11186297 | 0.86 | KDM4E (0.41) | KDM4EPTGS1PTGS2SMN1; SMN2TDP1 | |
| SCHEMBL11186287 | 0.86 | KDM4E (0.41) | KDM4EPTGS1PTGS2SMN1; SMN2TDP1 | |
| Benzophenone SCHEMBL11271133 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2PPARGPPARALMNATSHR | |
| SCHEMBL11175333 | 0.83 | MEN1 (0.38) | KDM4EPTGS1PTGS2SMN1; SMN2PPARG | |
| SCHEMBL11170156 | 0.83 | PTGS1 (0.40) | KDM4EPTGS1PTGS2GLI1GLI2 | |
| SCHEMBL11199131 | 0.83 | MEN1 (0.37) | KDM4EPTGS1PTGS2SMN1; SMN2PPARG | |
| SCHEMBL11191276 | 0.83 | MEN1 (0.37) | KDM4EPTGS1PTGS2SMN1; SMN2PPARG | |
| SCHEMBL11165820 | 0.83 | PTGS1 (0.38) | KDM4EPTGS1PTGS2SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |