Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17421815 | 0.87 | TOP1 (0.47) | TOP1 | |
| SCHEMBL1083220 | 0.87 | TOP1 (0.47) | TOP1 | |
| SCHEMBL11234405 | 0.87 | TOP1 (0.47) | TOP1 | |
| SCHEMBL11573698 | 0.87 | TOP1 (0.47) | TOP1 | |
| SCHEMBL11451513 | 0.87 | TOP1 (0.47) | TOP1 | |
| SCHEMBL1083217 | 0.87 | TOP1 (0.47) | TOP1 | |
| SCHEMBL11341829 | 0.86 | TOP1 (0.30) | TOP1 | |
| SCHEMBL11216573 | 0.85 | TOP1 (0.35) | TOP1 | |
| SCHEMBL11244757 | 0.84 | — | — | |
| SCHEMBL11883787 | 0.83 | PTGER2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390711-A | 16-Hydroxy-5-iodo-prostacyclin analogs of the 1 series | AMERICAN CYANAMID COMPANY (US) | 1983-06-28 | — | — | US | disclosed |
| US-4265904-A | BRONCHODILATOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4254285-A | 1-Hydroxymethyl-1-1-oxo prostane derivatives of the E and F series | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254036-A | 1-Hydroxymethyl-1-oxo-prostane-derivatives of the E, A and F-series | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4235797-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4235924-A | BRONCHODILATION, PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| EP-0015056-A1 | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E, A and F series | AMERICAN CYANAMID COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |
| US-4212969-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4202822-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4197245-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the A1 series | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |