Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083217 | 0.89 | TOP1 (0.47) | TOP1PTGER2TBXA2R | |
| SCHEMBL1083220 | 0.89 | TOP1 (0.47) | TOP1PTGER2TBXA2R | |
| SCHEMBL17421815 | 0.89 | TOP1 (0.47) | TOP1PTGER2TBXA2R | |
| SCHEMBL11451513 | 0.89 | TOP1 (0.47) | TOP1PTGER2TBXA2R | |
| SCHEMBL11234405 | 0.89 | TOP1 (0.47) | TOP1PTGER2TBXA2R | |
| SCHEMBL11573698 | 0.89 | TOP1 (0.47) | TOP1PTGER2TBXA2R | |
| SCHEMBL11182020 | 0.85 | TOP1 (0.33) | TOP1 | |
| SCHEMBL10686186 | 0.84 | ALDH1A1 (0.43) | TOP1TBXA2R | |
| SCHEMBL11883787 | 0.82 | PTGER2 (0.37) | ALOX5PTGER2TBXA2R | |
| SCHEMBL9460671 | 0.82 | PTGER2 (0.37) | ALOX5PTGER2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338252-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4283550-A | BRONCHODILATOR AGENTS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID (US) | 1981-08-11 | — | — | US | disclosed |
| US-4267361-A | HYPOTENSIVE, ANTIULCER, AND BRONCHODILATOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| US-4260805-A | BRONCHODILATOR AGENTS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4254275-A | BRONCHODILATORS, ANTIULCER, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254278-A | BRONCHODILATORS, ANTIULCER, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4250321-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4250323-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |