Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | GAA | P10253 | 7/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173698 | 0.82 | ALDH1A1 (0.55) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL16671107 | 0.82 | MAPT (0.63) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL3145055 | 0.82 | MAPT (0.53) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| Ammonia Solution, Strong SCHEMBL6698890 | 0.81 | MAPT (0.61) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL11532725 | 0.81 | ALDH1A1 (0.72) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL20632768 | 0.81 | ALDH1A1 (0.72) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL3011500 | 0.79 | MAPT (0.59) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL29008517 | 0.79 | MAPT (0.54) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL28367079 | 0.79 | MAPT (0.61) | MAPTGAAL3MBTL1MAPK1MEN1 | |
| SCHEMBL11527791 | 0.79 | ALDH1A1 (0.58) | MAPTGAAL3MBTL1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369325-A | ANTIPHLOGISTIC AND DIURETIC ACTIVITY | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-01-18 | — | — | US | disclosed |
| US-4284642-A | DIURETICS, ANTIPHLOGISTICS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-08-18 | — | — | US | disclosed |