Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 10/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 2/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179547 | 0.89 | PTPN1 (0.46) | PTGS1PTGS2PTPN1CA2BRD1 | |
| SCHEMBL11187994 | 0.87 | PTGS1 (0.56) | PTGS1PTGS2PTPN1HTR2CCA2 | |
| SCHEMBL11182596 | 0.85 | PTGS2 (0.54) | PTGS1PTGS2DRD2HTR2AHTR2C | |
| SCHEMBL11180303 | 0.74 | PTGS2 (0.52) | PTGS1PTGS2HTR2CBRD1BRPF1 | |
| SCHEMBL4381246 | 0.73 | PTGS1 (1.00) | PTGS1PTGS2 | |
| SCHEMBL11179885 | 0.73 | PTGS2 (0.53) | PTGS1PTGS2HTR2CBRD1BRPF1 | |
| SCHEMBL10823326 | 0.73 | PTGS2 (0.53) | PTGS1PTGS2HTR2CBRD1BRPF1 | |
| SCHEMBL11181649 | 0.72 | PTGS2 (0.47) | PTGS1PTGS2HTR2APGR | |
| SCHEMBL11186638 | 0.72 | PTGS2 (0.54) | PTGS1PTGS2HTR2CBRD1BRPF1 | |
| SCHEMBL11176650 | 0.72 | PTGS2 (0.59) | PTGS1PTGS2HTR2AHTR2CBRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009554-B1 | INDANYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-04-27 | — | — | EP | claimed |
| US-4244960-A | HERBICIDES OR ANTIINFLAMMATORY AGENTS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | claimed |
| EP-0009554-B1 | INDANYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-04-27 | — | — | EP | disclosed |
| US-4244960-A | HERBICIDES OR ANTIINFLAMMATORY AGENTS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | disclosed |