SCHEMBL1118503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1118480	0.86	HCAR3 (0.34)	PI4KBPI4KAHCAR3MAPTTP53
	SCHEMBL1117941	0.83	HCAR3 (0.41)	HCAR3
	SCHEMBL1783498	0.83	HCAR3 (0.43)	HCAR3MAPT
	SCHEMBL27857536	0.83	HCAR3 (0.39)	PI4KBPI4KAHCAR3MAPT
	SCHEMBL1780133	0.83	HCAR3 (0.39)	PI4KBHCAR3MAPTTP53
	SCHEMBL1117865	0.82	HCAR3 (0.42)	PI4KBHCAR3TP53
	SCHEMBL1117883	0.82	HCAR3 (0.41)	PI4KBPI4KAHCAR3TP53LCK
	SCHEMBL692405	0.81	HCAR3 (0.34)	PI4KBPI4KAHCAR3FPR3FPR2
	SCHEMBL1117879	0.80	HCAR3 (0.40)	HCAR3TP53
	SCHEMBL1783367	0.80	HCAR3 (0.37)	PI4KBHCAR3MAPTGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.