SCHEMBL111879

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL111124	0.92	CXCR3 (0.67)	CXCR3KCNH2NPSR1ALDH1A1MEN1
	SCHEMBL111638	0.91	CYP1A2 (0.65)	CXCR3KCNH2NPSR1ALDH1A1MEN1
	SCHEMBL112537	0.90	CXCR3 (0.61)	CXCR3KCNH2NPSR1ALDH1A1MEN1
	SCHEMBL164171	0.89	KDM4E (0.58)	CXCR3KCNH2NPSR1ALDH1A1MEN1
	SCHEMBL164307	0.86	CXCR3 (0.61)	CXCR3KCNH2NPSR1ALDH1A1HPGD
	SCHEMBL111117	0.85	TSHR (0.58)	CXCR3KCNH2NPSR1ALDH1A1MEN1
	SCHEMBL166583	0.84	CXCR3 (0.56)	CXCR3KCNH2NPSR1ALDH1A1KDM4E
	SCHEMBL112176	0.83	TSHR (0.58)	CXCR3KCNH2NPSR1ALDH1A1KDM4E
	SCHEMBL159867	0.83	CXCR3 (0.57)	CXCR3KCNH2ALDH1A1TSHRHSD17B10
	SCHEMBL112242	0.82	CXCR3 (0.54)	CXCR3KCNH2NPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.