Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 11/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL158635 | 0.95 | KAT2B (0.50) | KAT2BCA12CA1CA9GSK3A | |
| Hydrochloric Acid SCHEMBL11710311 | 0.95 | KAT2B (0.50) | KAT2BCA12CA1CA9GSK3A | |
| Hydrochloric Acid SCHEMBL155941 | 0.95 | KAT2B (0.50) | KAT2BCA12CA1CA9GSK3A | |
| Hydrochloric Acid SCHEMBL11190142 | 0.95 | KAT2B (0.50) | KAT2BCA12CA1CA9GSK3A | |
| Hydrochloric Acid SCHEMBL410386 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL11708723 | 0.95 | KAT2B (0.50) | KAT2BCA12CA1CA9GSK3A | |
| Hydrochloric Acid SCHEMBL11186626 | 0.95 | KAT2B (0.50) | KAT2BCA12CA1CA9GSK3A | |
| SCHEMBL20686 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL7939400 | 0.93 | — | — | |
| SCHEMBL7976030 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4396413-A | BACTERICIDES, FUNGICIDES, ALGICIDES | ROHM AND HAAS COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4241214-A | BACTERICIDE, FUNGICIDE AND ALGAECIDE | ROHM AND HAAS COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4150026-A | BACTERICIDES, FUNGICIDES, ALGICIDES | ROHM AND HAAS COMPANY (US) | 1979-04-17 | — | — | US | disclosed |