Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11188353 | 1.00 | ELANE (0.55) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL11189595 | 0.87 | ELANE (0.45) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL11190192 | 0.86 | ELANE (0.51) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL11187178 | 0.86 | ELANE (0.51) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL11189623 | 0.86 | ELANE (0.51) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL11189604 | 0.86 | ELANE (0.51) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL11189010 | 0.84 | ELANE (0.59) | ELANEMAPTKMT2AMMERAB9A | |
| SCHEMBL11189007 | 0.84 | ELANE (0.59) | ELANEMAPTKMT2AMMERAB9A | |
| SCHEMBL6414260 | 0.80 | ELANE (0.41) | ELANEMAPTADAM17KMT2AATM | |
| SCHEMBL7314482 | 0.79 | ELANE (0.56) | ELANEMAPTADAM17KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405638-A | ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1983-09-20 | — | — | US | claimed |
| US-4405638-A | ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1983-09-20 | — | — | US | disclosed |