Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187178 | 1.00 | ELANE (0.51) | ELANEACERAB9AHPGDMMP1 | |
| SCHEMBL11189604 | 0.86 | ELANE (0.51) | ELANEACERAB9AHPGDMMP1 | |
| SCHEMBL11189623 | 0.86 | ELANE (0.51) | ELANEACERAB9AHPGDMMP1 | |
| SCHEMBL11188353 | 0.86 | ELANE (0.55) | ELANEACERAB9AHPGDMAPT | |
| SCHEMBL11188356 | 0.86 | ELANE (0.55) | ELANEACERAB9AHPGDMAPT | |
| SCHEMBL11189007 | 0.80 | ELANE (0.59) | ELANERAB9AHPGDMAPTKMT2A | |
| SCHEMBL11189010 | 0.80 | ELANE (0.59) | ELANERAB9AHPGDMAPTKMT2A | |
| Stepronin SCHEMBL19339 | 0.77 | ELANE (0.56) | ELANEACERAB9AHPGDMAPT | |
| Stepronin SCHEMBL19338 | 0.77 | ELANE (0.56) | ELANEACERAB9AHPGDMAPT | |
| SCHEMBL7314482 | 0.76 | ELANE (0.56) | ELANERAB9AHPGDMAPTADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405638-A | ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1983-09-20 | — | — | US | claimed |