Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 3/20 | 0.37 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050554 | 0.79 | LMNA (0.44) | PDE10ATSHRDHODHLMNAHPGD | |
| SCHEMBL7050556 | 0.75 | LMNA (0.44) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL4882804 | 0.73 | PREP (0.50) | PDE10ATSHRFABP3FABP4PRNP | |
| SCHEMBL18988628 | 0.71 | PDE10A (0.47) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL27816594 | 0.71 | PDE10A (0.47) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL29042678 | 0.70 | PDE10A (0.46) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL10832124 | 0.70 | PDE10A (0.50) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL27663766 | 0.68 | PDE10A (0.49) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL3446771 | 0.68 | LMNA (0.52) | PDE10ATSHRDHODHFABP3FABP4 | |
| SCHEMBL2846662 | 0.68 | LMNA (0.52) | PDE10ATSHRDHODHFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401676-A | Novel α-amino acids | MERCK & CO., INC. (US) | 1983-08-30 | — | — | US | disclosed |