Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899321 | 0.84 | CYP2D6 (0.42) | PPARGPPARAPTGS2CYP1A2SRR | |
| SCHEMBL15899596 | 0.81 | PPARG (0.41) | PPARGPPARAFFAR1 | |
| SCHEMBL15899310 | 0.79 | MAPT (0.38) | PPARGPPARAPTGS2CYP1A2 | |
| SCHEMBL15899456 | 0.79 | TSHR (0.38) | PPARGPPARA | |
| SCHEMBL15899313 | 0.77 | MEN1 (0.40) | PPARGPPARAPTGS2 | |
| SCHEMBL15899559 | 0.76 | TSHR (0.39) | PPARGPPARA | |
| SCHEMBL8585344 | 0.76 | ABCB1 (0.52) | PTGS2 | |
| SCHEMBL1840846 | 0.75 | POLB (0.44) | PPARGPPARACYP1A2SRR | |
| SCHEMBL1840193 | 0.74 | PPARG (0.44) | PPARGPPARACYP1A2SRR | |
| SCHEMBL1835775 | 0.73 | PPARA (0.47) | PPARGPPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090196-A1 | Process for preparing dibenzyl-2-carboxylic acids and 3-substituted phthalides, as well as the resultant benzyl derivatives | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | claimed |
| EP-0090196-A1 | Process for preparing dibenzyl-2-carboxylic acids and 3-substituted phthalides, as well as the resultant benzyl derivatives | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |