Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899596 | 0.85 | PPARG (0.41) | POLBALPLALPGL3MBTL1PPARG | |
| SCHEMBL11189755 | 0.84 | PPARG (0.46) | PPARGCYP1A2PPARAPTGS2SRR | |
| SCHEMBL15899456 | 0.83 | TSHR (0.38) | CYP2D6CYP2C19POLBALPLALPG | |
| SCHEMBL15899310 | 0.83 | MAPT (0.38) | CYP2D6CYP2C19POLBALPLALPG | |
| SCHEMBL15899313 | 0.81 | MEN1 (0.40) | L3MBTL1PPARGPPARAPTGS2TSHR | |
| SCHEMBL15899559 | 0.80 | TSHR (0.39) | POLBALPLALPGL3MBTL1PPARG | |
| SCHEMBL27876145 | 0.76 | POLB (0.47) | CYP2D6CYP2C19ABCB1POLBALPL | |
| SCHEMBL2541275 | 0.76 | POLB (0.45) | CYP2C19POLBHTTNPSR1L3MBTL1 | |
| Bicarbonate SCHEMBL28105724 | 0.74 | EPHX1 (0.49) | POLBALPLALPGPPARGCYP1A2 | |
| SCHEMBL9979219 | 0.73 | TSHR (0.49) | CYP2C19L3MBTL1CYP1A2PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759552-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO LTD (JP) | 2016-02-10 | — | — | EP | disclosed |
| US-9243081-B2 | Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer | TOHO TITANIUM CO., LTD. (JP) | 2016-01-26 | — | — | US | disclosed |
| US-20140343237-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO., LTD. (JP) | 2014-11-20 | — | — | US | disclosed |
| EP-2759552-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | Toho Titanium CO., LTD. (JP) | 2014-07-30 | — | — | EP | disclosed |