Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26967929 | 0.96 | KDM4E (0.53) | HTTKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL85636 | 0.94 | HTT (0.49) | HTTKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL11191394 | 0.90 | HTT (0.43) | HTTKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL5371070 | 0.79 | HPGD (0.63) | HTTKDM4EGAAALDH1A1AKR1C3 | |
| SCHEMBL85584 | 0.79 | TDP1 (0.53) | HTTKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL5415229 | 0.78 | TDP1 (0.52) | HTTKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL11189999 | 0.77 | HSD17B10 (0.69) | KDM4EGAAALDH1A1HSD17B10AKR1C3 | |
| SCHEMBL11490102 | 0.75 | ALDH1A1 (0.40) | HTTKDM4EGAAALDH1A1HPGD | |
| SCHEMBL11495637 | 0.75 | CYP3A4 (0.43) | HTTKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL11496149 | 0.75 | HPGD (0.38) | HTTKDM4EGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394156-A | Novel N-phenyl-substituted N-heterocyclic compounds, their preparation and use in agents for regulating plant growth | CIBA-GEIGY CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| US-4294606-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1981-10-13 | — | — | US | disclosed |
| US-4208202-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |