Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 15/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990465 | 0.90 | NPY5R (0.95) | NPY5RNPC1RAB9AMAPTUSP30 | |
| SCHEMBL6992742 | 0.88 | NPY5R (1.00) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL6998436 | 0.88 | NPY5R (0.79) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL6992743 | 0.88 | NPY5R (1.00) | NPY5RNPC1RAB9AUSP30 | |
| SCHEMBL6996416 | 0.88 | NPY5R (0.82) | NPY5RNPC1RAB9AUSP30 | |
| SCHEMBL6993101 | 0.87 | NPY5R (0.84) | NPY5RNPC1RAB9AUSP30 | |
| SCHEMBL7000363 | 0.86 | NPY5R (1.00) | NPY5R | |
| SCHEMBL6999770 | 0.85 | NPY5R (0.77) | NPY5RNPC1RAB9AUSP30 | |
| SCHEMBL6998964 | 0.85 | NPY5R (0.78) | NPY5RNPC1RAB9AUSP30 | |
| SCHEMBL7000276 | 0.85 | NPY5R (0.78) | NPY5RNPC1RAB9AUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060037-A1 | USE OF NPY Y5 RECEPTOR ANTAGONISTS FOR THE PREVENTION OF PSYCHO-STIMULANT AND OPIOID ABUSE | UNIVERSITY OF COPENHAGEN (DK) | 2011-03-10 | — | — | US | claimed |
| EP-2280703-A1 | USE OF NPY Y5 RECEPTOR ANTAGONISTS FOR THE PREVENTION OF PSYCHOSTIMULANT AND OPIOID ABUSE | Københavns Universitet (University Of Copenhagen) (DK) | 2011-02-09 | — | — | EP | claimed |
| WO-2009112033-A1 | USE OF NPY Y5 RECEPTOR ANTAGONISTS FOR THE PREVENTION OF PSYCHOSTIMULANT AND OPIOID ABUSE | KØBENHAVNS UNIVERSITET (UNIVERSITY OF COPENHAGEN) (DK) | 2009-09-17 | — | — | WO | claimed |
| US-20110060037-A1 | USE OF NPY Y5 RECEPTOR ANTAGONISTS FOR THE PREVENTION OF PSYCHO-STIMULANT AND OPIOID ABUSE | UNIVERSITY OF COPENHAGEN (DK) | 2011-03-10 | — | — | US | disclosed |
| EP-2280703-A1 | USE OF NPY Y5 RECEPTOR ANTAGONISTS FOR THE PREVENTION OF PSYCHOSTIMULANT AND OPIOID ABUSE | Københavns Universitet (University Of Copenhagen) (DK) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009112033-A1 | USE OF NPY Y5 RECEPTOR ANTAGONISTS FOR THE PREVENTION OF PSYCHOSTIMULANT AND OPIOID ABUSE | KØBENHAVNS UNIVERSITET (UNIVERSITY OF COPENHAGEN) (DK) | 2009-09-17 | — | — | WO | disclosed |