Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.77 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995503 | 0.89 | NPY5R (0.73) | NPY5RUSP30NPC1RAB9AFOXO1 | |
| SCHEMBL6990465 | 0.87 | NPY5R (0.95) | NPY5RUSP30NPC1RAB9A | |
| SCHEMBL6992750 | 0.86 | NPY5R (0.72) | NPY5RUSP30NPC1RAB9AROCK1 | |
| SCHEMBL1119035 | 0.85 | NPY5R (1.00) | NPY5RUSP30NPC1RAB9A | |
| SCHEMBL6992743 | 0.85 | NPY5R (1.00) | NPY5RUSP30NPC1RAB9AROCK1 | |
| SCHEMBL6996416 | 0.85 | NPY5R (0.82) | NPY5RUSP30NPC1RAB9AROCK1 | |
| SCHEMBL6993101 | 0.84 | NPY5R (0.84) | NPY5RUSP30NPC1RAB9A | |
| SCHEMBL7000363 | 0.83 | NPY5R (1.00) | NPY5R | |
| SCHEMBL7000276 | 0.82 | NPY5R (0.78) | NPY5RUSP30NPC1RAB9AROCK1 | |
| SCHEMBL6998964 | 0.82 | NPY5R (0.78) | NPY5RUSP30NPC1RAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |