Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183280 | 0.86 | CYP3A4 (0.41) | CHRM2ADRA2AADRA2BADRA2CDRD3 | |
| SCHEMBL11181997 | 0.83 | NPC1 (0.41) | HTR1ACYP3A4LMNATSHRNR1I2 | |
| SCHEMBL11185351 | 0.82 | CYP3A4 (0.41) | CHRM2ADRA2AADRA2BADRA2CDRD3 | |
| SCHEMBL11188710 | 0.82 | AKR1B10 (0.41) | CHRM2HTR1AADRA2ASLC6A2ADRA1A | |
| SCHEMBL11182845 | 0.82 | PDE5A (0.39) | CYP3A4LMNATSHRNR1I2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11195539 | 0.81 | AKR1B10 (0.40) | CHRM2HTR1AADRA2ASLC6A2ADRA1A | |
| SCHEMBL11181993 | 0.81 | CYP3A4 (0.38) | HTR1ACYP3A4LMNATSHRNR1I2 | |
| SCHEMBL11180471 | 0.80 | MEN1 (0.40) | CHRM2HTR1AADRA2ASLC6A2ADRA1A | |
| SCHEMBL11178335 | 0.79 | PDE5A (0.38) | CHRM2ADRA2AADRA2BADRA2CDRD3 | |
| SCHEMBL11173677 | 0.78 | PTGDR2 (0.38) | CYP3A4LMNATSHRNR1I2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |