SCHEMBL11191978

SCHEMBL11191978

O=C(O)c1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(C(=O)O)cc3)c(C(=O)O)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
KDM4E B2RXH2 2/20 0.56
POLB P06746 1/20 0.56
MAPK1 P28482 1/20 0.56
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
FOLH1 Q04609 1/20 0.46
CFD P00746 2/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
PARP10 Q53GL7 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29266646 0.89 MAPT (0.52) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL11275036 0.88 ESR1 (0.50) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL11196552 0.87 KDM4E (0.58) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL10786832 0.86 ALDH1A1 (0.56) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL11204741 0.86 MAPT (0.49) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL18333400 0.84 KMT2A (0.55) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL10589091 0.83 KMT2A (0.48) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL15939509 0.83 MAPT (0.50) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL3712188 0.83 MAPT (0.55) MAPTKDM4EPOLBMAPK1KMT2A
SCHEMBL11269840 0.82 KMT2A (0.50) KMT2AALDH1A1CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4390683-A Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-06-28 US disclosed
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed