Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520194 | 0.83 | KDM4E (0.58) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL10347518 | 0.79 | KDM4E (0.54) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL895013 | 0.78 | KDM4E (0.52) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL6249450 | 0.77 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL29572496 | 0.76 | HPGD (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL9797513 | 0.76 | KDM4E (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL29861559 | 0.76 | KDM4E (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL18422 | 0.76 | HPGD (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL9183232 | 0.75 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL224818 | 0.75 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090216-A1 | Process and apparatus for the preparation of N,N'-bis-aroyl hydrazines | SIEMENS AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |