Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 4/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212920 | 1.00 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL11216415 | 0.99 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL11216413 | 0.99 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11221651 | 0.90 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11221662 | 0.90 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9003473 | 0.86 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9003471 | 0.86 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL8009106 | 0.85 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL8009107 | 0.85 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11214996 | 0.83 | ALDH1A1 (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | claimed |
| JP-58090534-A | — | — | None | — | — | JP | disclosed |
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |
| JP-S5890534-A | 2-AMINOPHENOL DERIVATIVE, ITS PRODUCTION, AND REMEDY CONTAINING THE SAME AS AN ACTIVE INGREDIENT | ONO PHARMACEUT CO LTD | 1983-05-30 | — | — | JP | disclosed |