Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197334 | 0.83 | NR3C2 (0.42) | KMT2APOLBMGLLPGRMAPT | |
| SCHEMBL11189827 | 0.81 | POLB (0.52) | ALDH1A1MEN1KMT2APOLBPGR | |
| SCHEMBL11188336 | 0.79 | PTGDR2 (0.46) | SMN1; SMN2MAPT | |
| SCHEMBL11195387 | 0.77 | POLB (0.38) | POLBPGR | |
| SCHEMBL11194975 | 0.77 | PTGDR2 (0.40) | ALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL11185885 | 0.76 | ALDH1A1 (0.44) | ELANEALDH1A1ADAMTS5PGR | |
| SCHEMBL27145357 | 0.65 | ELANE (0.50) | ELANEALDH1A1MEN1KMT2AMGLL | |
| SCHEMBL11196869 | 0.64 | AKR1B1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL27145564 | 0.62 | ELANE (0.47) | ELANEALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27145275 | 0.62 | ELANE (0.46) | ELANEALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079675-A1 | Oxazolidinedione derivatives | PFIZER INC. (US) | 1983-05-25 | — | — | EP | disclosed |