SCHEMBL111935

SCHEMBL111935

Cc1cc(N)c([N+](=O)[O-])cc1NCCO

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.52
▸ ALDH1A1 P00352 4/20 0.52
▸ TSHR P16473 3/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ RAB9A P51151 2/20 0.44
▸ LMNA P02545 1/20 0.43
▸ KAT2B Q92831 4/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ PKM P14618 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391950 1.00 MAPT (0.52) MAPTALDH1A1TSHRTDP1RAB9A
SCHEMBL2834179 0.92 MAPT (0.46) MAPTALDH1A1TSHRTDP1RAB9A
SCHEMBL11059627 0.92 MAPT (0.50) MAPTALDH1A1LMNAKAT2B
SCHEMBL11056141 0.87 MAPT (0.54) MAPTALDH1A1TSHRTDP1RAB9A
SCHEMBL30808005 0.87 MAPT (0.54) MAPTALDH1A1TSHRLMNAKAT2B
SCHEMBL112790 0.87 MAPT (0.54) MAPTALDH1A1TSHRLMNAKAT2B
SCHEMBL6151634 0.85 MAPT (0.52) MAPTALDH1A1TSHRTDP1LMNA
SCHEMBL21810594 0.85 MAPT (0.52) MAPTALDH1A1TSHRTDP1LMNA
SCHEMBL11056017 0.84 KAT2B (0.60) MAPTALDH1A1TDP1LMNAKAT2B
Bromide SCHEMBL10714879 0.84 MAPT (0.51) MAPTALDH1A1TSHRLMNAKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1437123-B2 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'ORÉAL (FR) 2017-11-08 — — EP claimed
EP-3034067-A1 Hair colouring compositions Unilever PLC (GB) 2016-06-22 — — EP claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 — — EP claimed
EP-0999823-B2 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME OREAL (FR) 2011-10-05 — — EP claimed
EP-1666095-B1 Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline OREAL (FR) 2010-05-19 — — EP claimed
EP-2158942-A2 Direct hair dye composition comprising insoluble oxygenated compounds and processes L'Oreal (FR) 2010-03-03 — — EP claimed
US-7651534-B2 Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition L'OREAL SA (FR) 2010-01-26 — — US claimed
EP-1757326-B1 Direct dying composition comprising insoluble oxygenated compounds and processes OREAL (FR) 2009-01-07 — — EP claimed
US-7452386-B2 Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline L'OREAL S.A. (FR) 2008-11-18 — — US claimed
EP-1432388-B1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL AG & CO KGAA (DE) 2008-06-18 — — EP claimed
EP-0673926-A1 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres L'OREAL (FR) 1995-09-27 — — EP claimed
EP-0646108-A1 HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES L'OREAL (FR) 1995-04-05 — — EP claimed
EP-0480829-B1 Hair dyeing composition containing anthraquinones OREAL (FR) 1994-04-06 — — EP claimed
WO-1994000414-A1 HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES L'OREAL (FR) 1994-01-06 — — WO claimed
US-5226924-A 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM L'OREAL (FR) 1993-07-13 — — US claimed
EP-0480829-A1 Hair dyeing composition containing anthraquinones L'OREAL (FR) 1992-04-15 — — EP claimed
US-4985042-A New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1991-01-15 — — US claimed
US-4954131-A Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1990-09-04 — — US claimed
US-4863480-A OXIDATION COLOR DYES THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) 1989-09-05 — — US claimed
US-4511360-A Dyeing compositions based on oxidation dyestuff precursors and on nitro benzene dyestuffs and their use for dyeing keratin fibres L'OREAL (FR) 1985-04-16 — — US claimed
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