SCHEMBL111946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL112077	0.91	CXCR3 (0.54)	CXCR3KCNH2ALDH1A1TSHRRAB9A
	SCHEMBL111164	0.91	CXCR3 (0.59)	CXCR3KCNH2ALDH1A1TSHRKMT2A
	SCHEMBL111873	0.90	CXCR3 (0.56)	CXCR3KCNH2ALDH1A1TSHRKMT2A
	SCHEMBL114797	0.89	CXCR3 (0.57)	CXCR3KCNH2ALDH1A1TSHRKMT2A
	SCHEMBL111473	0.88	CXCR3 (0.54)	CXCR3KCNH2ALDH1A1TSHRRAB9A
	SCHEMBL112603	0.88	CXCR3 (0.56)	CXCR3KCNH2ALDH1A1KDM4ETSHR
	SCHEMBL13075874	0.88	CXCR3 (0.56)	CXCR3KCNH2ALDH1A1TSHRSMN1; SMN2
	SCHEMBL109996	0.87	CXCR3 (0.55)	CXCR3KCNH2ALDH1A1KDM4ETSHR
	SCHEMBL111491	0.87	CXCR3 (0.61)	CXCR3KCNH2ALDH1A1KDM4ETSHR
	SCHEMBL111560	0.86	CXCR3 (0.56)	CXCR3KCNH2ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.