Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450031 | 0.83 | NOS3 (0.45) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL18160810 | 0.80 | NOS3 (0.42) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL825269 | 0.80 | NOS3 (0.42) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL12088700 | 0.79 | NOS3 (0.43) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL31256701 | 0.79 | NOS3 (0.43) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL28758399 | 0.76 | CYP1A2 (0.50) | NOS3NOS1NOS2CYP1A2ADORA2A | |
| SCHEMBL13957327 | 0.76 | CYP1A2 (0.50) | NOS3NOS1NOS2CYP1A2ADORA2A | |
| SCHEMBL20279304 | 0.76 | NOS3 (0.39) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL18157928 | 0.75 | NOS3 (0.38) | NOS3NOS1NOS2CXCR4PLAU | |
| SCHEMBL825251 | 0.75 | NOS3 (0.38) | NOS3NOS1NOS2CXCR4PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093915-A1 | Novel beta-lactam derivatives | GRUPPO LEPETIT S.P.A. (IT) | 1983-11-16 | — | — | EP | disclosed |