Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307497 | 0.97 | TYMS (0.58) | TYMSLMNASLC22A6FOLH1NFKB1 | |
| SCHEMBL454023 | 0.90 | LMNA (0.58) | TYMSLMNASLC22A6FOLH1NFKB1 | |
| Butane SCHEMBL7718806 | 0.88 | LPAR3 (0.54) | SLC22A6TSHRMEN1KMT2ATDP1 | |
| Alcohol SCHEMBL1487742 | 0.88 | LPAR3 (0.48) | TYMSSLC22A6TSHRMEN1KMT2A | |
| SCHEMBL4527282 | 0.87 | TSHR (0.60) | TYMSLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL4531743 | 0.87 | TSHR (0.60) | TYMSLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL4533190 | 0.87 | TSHR (0.60) | TYMSLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL20835969 | 0.87 | TSHR (0.60) | TYMSLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL4533111 | 0.87 | TSHR (0.60) | TYMSLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL4535332 | 0.87 | TSHR (0.60) | TYMSLMNASLC22A6NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390690-A | TETRAVALENT METAL | OCCIDENTAL RESEARCH CORP. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0010857-B1 | LAYERED OR AMORPHOUS ORGANOMETALLIC INORGANIC POLYMERS AND THEIR USE | OCCIDENTAL RESEARCH CORPORATION (US) | 1982-10-20 | — | — | EP | disclosed |
| US-4298723-A | ION EXCHANGERS, CATALYSTS, SORBENTS, CONTROLLED RELEASE, INTERCALATION COMPOUNDS | OCCIDENTAL RESEARCH CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0010857-A2 | Layered or amorphous organometallic inorganic polymers and their use | OCCIDENTAL RESEARCH CORPORATION (US) | 1980-05-14 | — | — | EP | disclosed |
| WO-1980000704-A1 | LAYERED OR AMORPHOUS ORGANOMETALLIC INORGANIC POLYMERS | OCCIDENTAL RES CORP (US) | 1980-04-17 | — | — | WO | disclosed |