Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198968 | 0.90 | CASR (0.56) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11195455 | 0.88 | EPHX2 (0.63) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11198671 | 0.82 | EPHX2 (0.63) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11193659 | 0.82 | EPHX2 (0.67) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11195367 | 0.80 | CASR (0.57) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL11192983 | 0.79 | EPHX2 (0.65) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11198011 | 0.79 | EPHX2 (0.56) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL5947875 | 0.78 | EPHX2 (1.00) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11204201 | 0.78 | EPHX2 (0.67) | EPHX2CYP2C9CYP2C19NPC1MEN1 | |
| SCHEMBL11204046 | 0.77 | CASR (0.54) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |