Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200284 | 0.88 | ALDH1A1 (0.50) | CASRALDH1A1MAPTHTTLMNA | |
| SCHEMBL11202190 | 0.86 | ALDH1A1 (0.47) | CASRALDH1A1KMT2AMAPTHTT | |
| SCHEMBL11198968 | 0.86 | CASR (0.56) | CASRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11204046 | 0.84 | CASR (0.54) | CASRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11199570 | 0.84 | CASR (0.48) | CASRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11196859 | 0.82 | LMNA (0.49) | CASRALDH1A1HTTLMNANPSR1 | |
| SCHEMBL11196992 | 0.80 | EPHX2 (0.63) | CASRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11200327 | 0.80 | CNR1 (0.50) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL11203072 | 0.80 | ALDH1A1 (0.45) | CASRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11200290 | 0.79 | CNR1 (0.44) | CASRALDH1A1HTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |