Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543604 | 0.89 | TAAR1 (0.57) | TAAR1SLC6A3DRD2SLC6A4DAO | |
| SCHEMBL8088839 | 0.81 | MEN1 (0.57) | TAAR1SLC6A3DRD2SLC6A4MIF | |
| SCHEMBL17117518 | 0.79 | TAAR1 (0.59) | TAAR1SLC6A3DRD2SLC6A4DAO | |
| SCHEMBL1047725 | 0.79 | TAAR1 (0.59) | TAAR1SLC6A3DRD2SLC6A4DAO | |
| SCHEMBL8827723 | 0.78 | XIAP (0.46) | — | |
| SCHEMBL5539186 | 0.78 | TAAR1 (0.53) | TAAR1DAO | |
| SCHEMBL6083770 | 0.78 | TAAR1 (0.53) | TAAR1DAOIDO1HTR2B | |
| SCHEMBL3371633 | 0.77 | TAAR1 (0.74) | TAAR1SLC6A3DRD2SLC6A4DAO | |
| SCHEMBL1043920 | 0.77 | TAAR1 (0.57) | TAAR1SLC6A3DRD2SLC6A4DAO | |
| SCHEMBL7676725 | 0.76 | AGXT (0.44) | AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |